So, what is GenoCAD, exactly?
GenoCAD is a design tool that uses collections or libraries of genetic parts, as well as explicit design rules describing how these parts should be combined, to engineer genetic constructs. Sets of design rules are called grammars. Genetic grammars underpin GenoCAD’s design environment, which is a step-by-step wizard that guides users through the process of designing complex genetic constructs. When a design is completed, its DNA sequence can be exported using standard formats.
How does GenoCAD work?
GenoCAD can be used in a variety of ways. In this video we demonstrate a straightforward way to think about GenoCAD. First, a user develops a grammar that is appropriate for a particular scientific hypothesis or engineering application and is informed by domain expertise. After the grammar is built, it needs to be populated with genetic parts, which the user imports into GenoCAD. Once a grammar has been developed and parts have been added to it, a user can design a construct using the wizard. Certain designed constructs can even be simulated. In future videos, we will demonstrate how to use each of these modules.
GenoCAD provides an environment to easily design constructs according to previously developed grammars. This approach reduces errors that are common in ad hoc genetic design workflows, thereby increasing reproducibility and productivity. From simple tasks like managing hundreds of parts to sophisticated functions such as simulating the in vivo behavior of designed constructs, GenoCAD gives you the tools you need.
If you haven't already, be sure to sign up for GenoCAD! Once your username and password are set, please log in and take a look around. In our next video, we will demonstrate how to design DNA constructs using GenoCAD!