GenoCAD was initially developed at the Virginia Bioinformatics Institute at Virginia Tech with support from the National Science Foundation under Grant No. EF-0850100. GenoFAB, LLC was setup in 2013 to ensure the sustainability of this resource. GenoFAB is now providing a commercial version of GenoCAD derived from the open source code based released by Virginia Tech.


2007: GenoCAD launches as a research project from the Peccoud Lab at the Virginia Bioinformatics Institute. In October, Peccoud and colleagues describe the basis for GenoCAD, rooted in context-free grammars, in a Bioinformatics paper titled "A syntactic model to design and verify synthetic genetic constructs derived from standard biological parts."

2009: The Peccoud Lab publishes "Writing DNA with GenoCAD" in Nucleic Acids Research. The paper describes the GenoCAD platform in detail, explaining both the grammar-based methodology behind it and the software's features. The paper spends time on how GenoCAD can be used to "design protein expression vectors, artificial gene networks and other genetic constructs."

2011:  Peccoud and colleagues publish "A step-by-step introduction to rule-based design of synthetic genetic constructs using GenoCAD" in the journal Methods in Enzymology.

2013: Support for development of the GenoCAD software shifts from the NSF grant to private funding

Late 2014-Early 2015: The GenoFAB, LLC team is assembled, bringing together individuals with backgrounds in synthetic biology, cell biology, bioinformatics, software development, and science communications to move the company and its flagship DNA design software platform forward.

May 2015: GenoCAD leaves its longtime home at, where it was hosted by the Virginia Bioinformatics Institute, and moves to its own dedicated servers at

May 2015: Peccoud and his research collaborators publish a paper in Nucleic Acids Research called "GenoLIB: a database of biological parts derived from a library of common plasmid features." The paper describes development and annotation of a massive set of DNA parts from almost 2000 available plasmids. This data set is built for use in synthetic biology and parts-based design, and was incorporated into a new GenoCAD library following publication.

June 2015: GenoCAD moves its headquarters from the New Orleans BioInnovation Center to the heart of San Francisco.